Granulated vs. Direct Blend Powders: Which Is Better for Sachets?
Powder that clumps, sticks, or separates during filling can derail production and compromise quality. The foundation of a reliable sachet product starts with one key decision: granulation or direct blend. Granulation converts fine powders into denser, flowable granules using wet or dry processes. Direct blend powders are mixed and filled without modification. Here is a […]
Challenges in Manufacturing Multi-Component Formulas With Uniform Potency
Getting multiple active ingredients to work together in one dose is no small task. Multi-component drug products, such as fixed-dose combinations, supplements, and therapies that include multiple APIs, offer clear advantages. However, as the number of active ingredients increases, so does the complexity of manufacturing. As each component is introduced, the challenge of achieving uniform […]
Powder Blending and Granulation: Process Optimization for Manufacturing
A drug is only as good as the process behind it, and even the most potent compound can fail without a solid foundation in powder processing. Before a tablet reaches a patient or passes quality control, it must be made from powders that flow, compress, and hold together consistently. That is why, in pharmaceutical manufacturing, […]