Granulated vs. Direct Blend Powders: Which Is Better for Sachets?
Powder that clumps, sticks, or separates during filling can derail production and compromise quality. The foundation of a reliable sachet product starts with one key decision: granulation or direct blend. Granulation converts fine powders into denser, flowable granules using wet or dry processes. Direct blend powders are mixed and filled without modification. Here is a […]
Why Is Powder Blend and Flow Important for Manufacturing?
The way powder flows and blends directly affects product quality, regulatory compliance, and overall manufacturing efficiency. Consistency. That is what every pharmaceutical product depends on, especially when working with powders. For small pharmaceutical companies, limited batch sizes and tighter budgets leave very little room for waste, inefficiency, or failed batches. Understanding and controlling powder blend […]
What is Freeze thaw (Thermal cycling) study?
A freeze-thaw study is a type of stress test performed on liquid formulations to evaluate how finished dosage forms react to repeated cycles of freezing and thawing. For example, when pharmaceutical suspensions formulations or emulsions freeze, they lose their structural characteristics that maintain their properties. Upon thawing, the drug substance may not redisperse properly or may […]