SBIR Grants for Early-Stage Drug Development
Small Business Innovation Research (SBIR) grants for early-stage drug development offer start-up biopharma companies seed funding that helps turn their innovative drug therapy concepts into successful FDA drug development programs. Bringing a new drug to the market can be quite complex and expensive, especially for small pharmaceutical companies. That is where the SBIR and Small […]
Key Considerations in Suppository Formulation Development
Suppositories are solid forms of medicine that are designed to be inserted into bodily openings like the rectum, vagina, or urethra. Once inside the body, they melt or dissolve to release the active ingredients for absorption. When it comes to creating the perfect suppository, it isn’t just about mixing ingredients together; it’s also about achieving […]
Solid State Properties of Drugs
A thorough understanding of the solid state properties of drugs is vital for pharma companies that want to develop effective pharmaceuticals. These properties affect how stable, soluble, and bioavailable a drug will be. In essence, a good grasp of how active pharmaceutical ingredients (APIs) behave in their solid form is important for making effective drugs. […]
What is Formulation Development?
Pharmaceutical formulation development is the science of developing a dosage form that contains an active ingredient along with inactive ingredients that can be administered to a patient. Examples of dosage forms include oral tablets, oral capsules, oral solutions, oral suspensions, ophthalmic drops, topical semisolids such as creams and ointments, or injections. Why is formulation development […]
Orally Disintegrating Tablets (ODTs): A Quick Guide to Fast-Dissolving Medication
Orally disintegrating tablets (ODTs) are solid dosage forms that rapidly dissolve in the mouth without the need for water, typically within seconds to a minute. They are designed to improve patient compliance, especially for those with difficulty swallowing, by providing a convenient and easy-to-administer alternative to traditional tablets. In this article, we’ll explore what ODTs […]
What Is GLP-1: Understanding Its Role in Formulation Development
What is GLP-1, and why is it important in formulation development? Glucagon-like peptide-1, or GLP-1, is a hormone that helps regulate blood sugar, manage appetite, and support digestion. Certain medications, known as GLP-1 agonists, mimic these functions and are especially helpful for people with type 2 diabetes or obesity. How can pharmaceutical companies ensure they […]
Chewable Tablets: A Guide to Formulation and Development
Chewable tablets are solid oral dosage forms designed to be chewed and swallowed rather than taken whole. They are particularly beneficial for children and those who have difficulty swallowing large tablets. These dosage forms are palatable and conveniently deliver the active ingredients found in vitamins, antibiotics, and analgesics. This guide explores their formulation and development […]
Oral Liquids – A Comprehensive Guide
Oral liquids are an essential part of modern healthcare; they offer patients a convenient way to take their medications. These pharmaceutical formulations disperse active ingredients through a liquid medium and come in various forms, such as suspensions, solutions, and syrups. They are easy to administer, making them an effective alternative for patients who struggle with […]
Taste Masking in Oral liquids
Oral liquids such as syrups and suspensions are the preferred dosage form for pediatric and geriatric patients due to their ease of administration. Swallowing a tablet can be difficult for an infant or an elderly person and injectables usually require a qualified person to administer the drug. Patient compliance in both these drastically decreases if […]
Formulating Fixed-Dose Combination (FDC) Drugs: Innovation through bilayer tablet technology
Bilayer tablets consist of two or more different layers compressed together to form a single tablet. Bilayer tablets are gaining popularity due to their ability to administer multiple active ingredients in one single dosage form. Patients prefer a simple dosing regimen rather than taking multiple different pills throughout the day. Bilayer tablets can help in […]